Archive for: Mechanism of Action

Mechanism of RNA recognition by a Musashi RNA-binding protein.

Interplay between the RNA binding-protein Musashi and developmental signaling pathways.

Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation.

Structure of Musashi1 in a complex with target RNA: the role of aromatic stacking interactions

Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation

Context-dependent regulation of Musashi-mediated mRNA translation and cell cycle regulation

Regulation of myeloid leukaemia by the cell-fate determinant Musashi

Genomic analyses of Musashi1 downstream targets show a strong association with cancer-related processes

Neural RNA-binding protein Musashi1 inhibits translation initiation by competing with eIF4G for PABP

The RNA-binding protein Musashi-1 regulates neural development through the translational repression of p21WAF-1